The cave of Melidoni, or Gerontospilios as the locals use to call it is found at a distance of 31 kilometers far from Rethymnon at the East and 2 kilometers far from the village of Melidoni at the Northwest. The cave is open to visitors and presents both spelaeological and archaeological interest.

The cave played an important role during the revolts of Cretan people against the Ottoman domination as it served as a place to hide for the warriors and a refuge for the weak population. It is in such an occasion in January of 1824 that 370 people from the area, mainly women and children, were extinguished by the Ottomans. A memorial sarcophagus, containing the skeletal remains of these people is found in the first hall of the cave.